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Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million individuals in England, Northern Ireland, Scotland, and Wales

Older people, those with multimorbidity, and those with specific underlying health conditions remain at increased risk of COVID-19 hospitalisation and death after the initial vaccine booster and should, therefore, be prioritised for additional boosters, including novel optimised versions, and the increasing array of COVID-19 therapeutics.

United kingdomNorthern irelandCity ofAfshin dastafshanLaura gonzalez riendaMaria georgiouPaul mossPam mcveighVicky hammersleyJames pickettSnehan anandWendy inglis humphreySamantha lycettSumedha asnani chetalDave kellyRachel byford

Characterising adults in Scotland who are not vaccinated against COVID-19

By Aug 10, 2022, 3 497 208 of the estimated 4·4 million adults living in Scotland had received three doses of a COVID-19 vaccine. However, a proportion of the adult population remains unvaccinated (defined as no record of any vaccine being administered) and susceptible to severe COVID-19 outcomes. Characterising this population can help to understand gaps in vaccine coverage and determinants of vaccine hesitancy and could support targeted public health messaging. Unlike the vaccinated population, on whom information is gathered at the point of vaccination, current estimates of the unvaccinated population are calculated using general practitioner (GP) records.

Glasgow cityUnited kingdomCity ofDave kelly albasoftJamie wilsonMaria georgiouVicky hammersleyWendy inglis humphreyMorna cooteAmanda burridgeUnited kingdom health security agencyMegan gorman public health scotlandScience officeNational health serviceUniversity of edinburghNational records of scotland

First dose ChAdOx1 and BNT162b2 COVID-19 vaccinations and cerebral venous sinus thrombosis: A pooled self-controlled case series study of 11 6 million individuals in England, Scotland, and Wales

In a pooled self-controlled case series study, Steven Kerr and colleagues assess the association between first dose ChAdOx1 and BNT162b2 COVID-19 vaccination with cerebral venous sinus thrombosis in England, Scotland and Wales.

United statesUnited kingdomNorthern irelandOxford astrazeneca chadoxLaura gonzalez riendaMaria georgiouAstra zenecaVicky hammersleyJames pickettWendy inglis humphreySuzannec cannegieterOxford astrazenecaDave kellyR al shahi salmanHealth research councilAdministrative data research wales

Solving crosswords and number puzzles may make your brain sharper at old age

Older people who regularly solve crosswords and Sudoku have the mental abilities of those ten years their junior.

United kingdomJames pickettAnne corbettUniversity of exeter medical schoolUnited kingdom alzheimer societyInternational journal of geriatric psychiatryExeter medical schoolInternational journalGeriatric psychiatryBronx aging study

Remembering Adyn Pickett, a boy who touched people s hearts and souls

Remembering Adyn Pickett, a boy who touched people s hearts and souls
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