Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million individuals in England, Northern Ireland, Scotland, and Wales

Older people, those with multimorbidity, and those with specific underlying health
conditions remain at increased risk of COVID-19 hospitalisation and death after the
initial vaccine booster and should, therefore, be prioritised for additional boosters,
including novel optimised versions, and the increasing array of COVID-19 therapeutics.

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