Date Time
Tumor microenvironment helps aggressive lymphomas
The environment surrounding the cancerous cells of a lymphoma tumor has a strong influence on the progression of these blood-cell cancers and their responses to therapies, according to a new study by Weill Cornell Medicine investigators.
Measuring this molecular and cellular environment, or “microenvironment,” appears to represent a new type of precision-medicine approach to lymphoma classification and treatment. CoRus13/Creative Commons
Diffuse large B-cell lymphoma.
The team analyzed the patterns of gene activity in tumor samples taken from the lymph nodes of thousands of lymphoma patients. They found that the cells within these tumors, which include both cancer cells and healthy cells, produce molecules that collectively constitute a distinct microenvironment for the tumors, influencing their biology and growth.
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Insight into role of aging in response to SARS-CoV-2 infection
Older adults and those with underlying medical conditions are at a higher risk of developing severe coronavirus disease (COVID-19), the illness caused by the infectious agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Previous studies have shown that older people are at a higher risk of COVID-19 because of physiological changes that come with aging and potential comorbidities, including diabetes, hypertension, and heart problems.
Researchers at the University of California, Irvine set out to determine the differences between young people and older adults regarding their host responses against SARS-CoV-2. The team revealed that independent of disease severity, COVID-19 was linked to a significant shift in plasma inflammatory factors. The research is posted to the pre-print server
Washington [US], January 19 (ANI): In an effort to address a major challenge when analyzing large single-cell RNA-sequencing datasets, researchers from the University of Texas MD Anderson Cancer Center have developed a new computational technique to accurately differentiate between data from cancer cells and the variety of normal cells found within tumor samples.
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