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An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the âguardian of the genomeâ for its ability to repair DNA damage or destroy cancerous cells. Published today in Nature Communications, a study of the direct interaction between p53 and the green tea compound, epigallocatechin gallate (EGCG), points to a new target for cancer drug discovery.
âBoth p53 and EGCG molecules are extremely interesting. Mutations in p53 are found in over 50% of human cancer, while EGCG is the major anti-oxidant in green tea, a popular beverage worldwide,â said Chunyu Wang, corresponding author and a professor of biological sciences at Rensselaer Polytechnic Institute. âNow we find that there is a previously unknown, direct interaction between the two, which points to a new path for developing anti-cancer drugs. Our work helps to explain how EGCG is able to boost p53âs anti-cancer activity, opening the door to dev
Major antioxidant in green tea may increase levels of natural anti-cancer protein
An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the guardian of the genome for its ability to repair DNA damage or destroy cancerous cells. Published today in
Nature Communications, a study of the direct interaction between p53 and the green tea compound, epigallocatechin gallate (EGCG), points to a new target for cancer drug discovery.
Both p53 and EGCG molecules are extremely interesting. Mutations in p53 are found in over 50% of human cancer, while EGCG is the major anti-oxidant in green tea, a popular beverage worldwide. Now we find that there is a previously unknown, direct interaction between the two, which points to a new path for developing anti-cancer drugs. Our work helps to explain how EGCG is able to boost p53 s anti-cancer activity, opening the door to developing drugs with EGCG-like compounds.
Green tea compound aids tumour-suppressing ohiostandard.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from ohiostandard.com Daily Mail and Mail on Sunday newspapers.
New York [US], February 13 (ANI): An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the 'guardian of the genome' for its ability to repair DNA damage or destroy cancerous cells.