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Experimental drug may slow the progression of atherosclerosis

An experimental drug already tested as a potential treatment for cancer, lung disease, and Alzheimer's disease may slow the progression of atherosclerosis that leads to heart disease, a new study shows.

New yorkUnited statesPeik sean chongSimon koplevMinji jeonChristopher hillNatalia eberhardtAdam ghotbiRavneet kaurYannick cyrPeter fariesAvi maayanKen sakuraiChiara giannarelliPauline muryLily ramsey

Experimental Cancer Drug Slows Inflammation in Animal Models of Heart Disease

Experimental Cancer Drug Slows Inflammation in Animal Models of Heart Disease
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Letizia amadoriChiara giannarelliGrossman school of medicineNature cardiovascular researchLangone healthLibrary of integrated networkIntegrated network based cellular signatures

Experimental Cancer Drug May Slow Inflammation Linked to Heart Disease

Experimental Cancer Drug May Slow Inflammation Linked to Heart Disease
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New yorkUnited statesSimon koplevMinji jeonAvi maayanNicolas fernandezAdeeb rahmanNayaab kahnRaphael solerAdam ghotbiKen sakuraiPeter fariesRavneet kaurSwathy sajjaChristopher hillLetizia amadori

MyJournals org - Science - Drug repositioning prediction for psoriasis using the adverse event reporting database (Frontiers in Medicine)

MyJournals.org - Science - Drug repositioning prediction for psoriasis using the adverse event reporting database (Frontiers in Medicine)

United statesDrug administration adverse event reporting systemChemical european molecular biology laboratory chembl conclusioninverseLibrary of integrated cellular signaturesUnited states foodGene expression omnibusIntegrated network based cellular signaturesChemical european molecular biology laboratory

A systems approach points to a therapeutic role for retinoids in asparaginase-associated pancreatitis

A systems approach points to a therapeutic role for retinoids in asparaginase-associated pancreatitis
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United statesInternational classification of diseaseLibrary of integrated cellular signaturesNational institutes of healthDana farber cancer instituteConnectivity mapNational institutesIntegrated network based cellular signaturesInternational classificationSupplementary materialsPairwise spearman