Patients who underwent amputation due to a diabetic foot event had a greater risk for early death regardless of the presence or absence of ulcers or gangrene before the amputation.
Insulin resistance may increase the risk for cardiovascular outcomes but not kidney outcomes in patients with type 2 diabetes and chronic kidney disease.
Look AHEAD trial participants who achieved type 2 diabetes remission had lower risks for CKD and CVD, in a dose-response relationship by remission duration.
While tirzepatide has bagged FDA approval for treating T2D and for weight loss, the critical question remains can it also safeguard the kidneys, a key objective in diabetes care?