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Searching for Surrogates: The Effort to Speed Up Drug Trials

Identifying surrogate endpoints for use in clinical trials that strongly predict clinical outcomes such as improved survival and quality of life is challenging.

United statesNational institutes of healthSan franciscoAmaru kishanHiddol heerspinkVincent plancheJuliaa beaverCarol taylor burdsLos angelesKarin hoelzerFabio confortiRichard pazdurAnushka waliaEmersony chenGinny beakesFady ghali

Searching for Surrogates: The Effort to Speed Up Drug Trials

Identifying surrogate endpoints for use in clinical trials that strongly predict clinical outcomes such as improved survival and quality of life is challenging.

United statesNational institutes of healthSan franciscoFabio confortiVincent plancheFady ghaliKarin hoelzerGinny beakesCarol taylor burdsAmaru kishanRichard pazdurHiddol heerspinkAnushka waliaLos angelesEmersony chenJuliaa beaver

Study Supports Total GFR Slope as a Surrogate Endpoint in Clinical Trials

GFR slope holds promise as a surrogate endpoint for clinical trials of new drugs for chronic kidney disease (CKD).

New south walesHiddol heerspinkUniversity medical center groningenGeorge institute of global healthEuropean renal associationGeorge instituteGlobal health

ADA: Tirzepatide Improves Kidney Outcomes in T2DM With Increased CV Risk

Fewer renal complications seen with tirzepatide versus insulin glargine in adults with T2D and increased cardiovascular risk.

United statesEli lillyHiddol heerspinkAmerican diabetes associationUniversity medical center groningenHealthday news

Tirzepatide Slowed Progression of Chronic Kidney Disease in Patients with Type 2 Diabetes with Increased Cardiovascular Risk

/PRNewswire/ A pre-specified exploratory analysis from the SURPASS-4 trial showed tirzepatide, a novel once-weekly medication for the treatment of diabetes,.

United statesInstagram amdiabetesassnDaisy diazFacebook asociaciHiddol heerspinkFacebook american diabetes associationUniversity medical center groningenErnestn morial convention centerAmerican diabetes associationLinkedin american diabetes associationTop research abstracts withHazard ratioDiabetic kidney diseaseTop research abstractsSelect abstract presentationKidney outcomes

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