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Trends in the prevalence of Hepatitis C infection during pregnancy and maternal-infant outcomes in the US, 1998 to 2018

1. The prevalence of Hepatitis C infection during pregnancy increased between 1998 and 2018, coinciding with the opioid epidemic. 2. Individuals of White race, lower socioeconomic status, and a history of substance use were more likely to be infected with Hepatitis C during pregnancy. 3. Hepatitis C Infection was associated with a greater risk of

Expensive Treatment Associated With Low Retention Rates Among Patients With Hepatic Encephalopathy

#VisualAbstract: Primary hepatectomy may be superior to conventional hepatectomy for primary hepatocellular carcinoma

1. Patients with primary hepatocellular carcinoma randomized to receive primary hepatectomy versus conventional hepatectomy had less operation time, fewer complications, higher immune function post-op, and lower rates of recurrence at 3 years, amongst other advantages. Evidence Rating Level: 1 (Excellent) For patients with primary liver cancer, precision hepatectomy is a novel surgical approach that aims to

Gene therapy improves bilirubin levels in Crigler-Najjar syndrome

1. In this randomized controlled trial, a high dose of GNT0003 gene therapy was associated with decreased serum bilirubin and need for phototherapy. 2. The most common adverse events associated with GNT0003 were headache and liver enzyme elevations. Evidence Rating Level: 1 (Excellent) Study Rundown: Crigler-Najjar syndrome is a rare recessive disorder resulting in loss

High cost of hepatic encephalopathy treatment may lead to medication non-adherence

Researchers from the University of Minnesota Medical School and College of Pharmacy have found that high costs for hepatic encephalopathy treatment in patients with end-stage liver disease were associated with decreased treatment retention for patients.

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