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Background: Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a prothrombotic state, but long-term effects of COVID-19 on incidence of vascular diseases are unclea.
Older people, those with multimorbidity, and those with specific underlying health
conditions remain at increased risk of COVID-19 hospitalisation and death after the
initial vaccine booster and should, therefore, be prioritised for additional boosters,
including novel optimised versions, and the increasing array of COVID-19 therapeutics.
By Aug 10, 2022, 3 497 208 of the estimated 4·4 million adults living in Scotland
had received three doses of a COVID-19 vaccine. However, a proportion of the adult
population remains unvaccinated (defined as no record of any vaccine being administered)
and susceptible to severe COVID-19 outcomes. Characterising this population can help
to understand gaps in vaccine coverage and determinants of vaccine hesitancy and could
support targeted public health messaging. Unlike the vaccinated population, on whom
information is gathered at the point of vaccination, current estimates of the unvaccinated
population are calculated using general practitioner (GP) records.