Highlights from early- and late-stage pipeline include combination data for cornerstone therapies BRUKINSA and tislelizumab early results for OX40 agonist BGB-A445 and BCL-2 inhibitor. | May 25, 2023
Highlights from early- and late-stage pipeline include combination data for cornerstone therapies BRUKINSA and tislelizumab early results for OX40 agonist BGB-A445 and BCL-2 inhibitor BGB-11417 BeiGene
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IMAGE: Design and fabrication principle of the MAIPAMs. (A) Schematic of the skeleton-free muscular hydrostats. (B) The morphology of the designed MAIPAMs. (C) Multiple-mode actuations of the MAIPAMs. (D) Schematic of. view more
Credit: @Science China Press
Biological organisms (such as elephant trunks, octopus tentacles, and human tongues) show remarkable dexterity and self-adaptation in unstructured environments, relying on the multiple-mode actuations of the skeleton-free muscular hydrostats. In general, muscular hydrostats mainly consist of well-ranged active 3D muscle-fiber arrays bundled by passive connective tissues (Fig. 1A). By selectively actuating the active 3D muscle-fiber arrays, muscular hydrostats can generate elongation, bending, contraction and twisting. Producing such multiple-mode actuation of muscular hydrostats is an interesting but long-lasting challenge in the field of robotics.