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In venous thromboembolism, a blood clot usually forms in the deep veins of the legs or pelvis. This is known as deep vein thrombosis, and the blood clot can dislodge from these sites, resulting in pulmonary embolism.
In 2020, the National Institute for Health and Care Excellence (NICE) first published guidance on the diagnosis and management of venous thromboembolic disease.1 Since then, new evidence has emerged which indicates that people with covid-19 have a higher risk of developing venous thromboembolism and elevated D-dimer levels, and that this risk increased with severity of covid-19 infection. In the 2021 British Thoracic Society guidelines on venous thromboembolism in patients with covid-19, one meta-analysis of 49 studies reported an incidence of venous thromboembolism of 17% in people with covid-19, and that the incidence was higher in patients in intensive care (28%) compared with those on a medical ward (7%).2 D-dimer, a protein fragment that ca
When: 11 Oct. 2023, 13:00–14:00 CEST, Ebola and Marburg Haemorrhagic fever are both severe and highly fatal diseases. They are caused by different viruses but of the same family. Ebola disease and Marburg disease outbreaks continue to occur in Africa, with increased frequency. In addition to resulting in high mortality and morbidity, the outbreaks generate fear and mistrust about the response activities within the communities affected.
### What you need to know
Type 2 diabetes mellitus (T2DM) in children and young people (aged under 18 years) is a more aggressive disease than in older adults and is associated with higher risk of severe long term and potentially life threatening complications (eg, cardiovascular disease, renal disease) compared with other types of diabetes. The worldwide prevalence and annual incidence of T2DM in children and young people is increasing,1 and the National Paediatric Diabetes Audit (NPDA) of England and Wales from 2019-20 showed a prevalence and incidence of 4.5 and 1.7 per 100 000 people 15 years and younger, respectively, and 222 new diagnoses.2 Over the past three years, prevalence has increased by one third, and many children and young people with T2DM are not currently receiving care from paediatric diabetes teams.3 Children and young people who are living with obesity, are of ethnic minority background, and reside in the most deprived areas of the UK, are at increased risk of h