Provenzano Lab, University of Minnesota
Cancer cells (shown in green) often align their movement to collagen fibers (shown in white). Understanding how cells move is key to preventing cancer spread throughout the body.
Tranquillo group, University of Minnesota
Human skin cells entrapped in an aligned fibrin gel exhibit contact guidance by orienting themselves along the aligned protein fibers in tissues.
Tranquillo group, University of Minnesota
A University of Minnesota study provides the first proof of a 1982 theory that the mechanical resistance (the stiffness of the fibers) plays a key role in controlling the movement of cells. The discovery could have a major impact on regenerative medicine and cancer research.
New study provides clues to decades-old mystery about cell movement
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New study provides clues to decades-old mystery about cell movement
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VIDEO: This video shows a University of Minnesota lab-created tri-tube heart valve being tested under heart condition for function in ViVitro pulse duplicator system. view more
Credit: Syedain, et al., Tranquillo Lab, University of Minnesota; Science Translational Medicine: https://z.umn.edu/pediatricheartvalves
A groundbreaking new study led by University of Minnesota Twin Cities researchers from both the College of Science and Engineering and the Medical School shows for the first time that lab-created heart valves implanted in young lambs for a year were capable of growth within the recipient. The valves also showed reduced calcification and improved blood flow function compared to animal-derived valves currently used when tested in the same growing lamb model.