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Queensland researchers have discovered that a mutation allows some E. coli bacteria to cause severe disease in people while other bacteria are harmless, a finding that could help to combat antibiotic resistance.
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Researchers discover bacteria can make DNA using urine
Bacteria (round spheres) on the surface of the bladder where they encounter urine to make their DNA. (Image: Glen Ulett)
Streptococcus, a bacterium that causes painful human urinary tract infections can generate new DNA using human urine, researchers at Griffith University have found.
Dr Matthew Sullivan and colleagues from the School of Medical Science discovered the bacterium, which often infects healthy humans, has specialised to make the chemical building blocks for its own DNA with important ramifications for its capacity to cause infection and disease.
In the study, published in the International Society of Microbial Ecology (ISME) Journal, the researchers carved out particular pieces of the bacteria’s genome to show that a specialised gene in the bacterium allows it to exploit natural chemicals found in urine as a way to produce new DNA.