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Researchers design micro-sized capsules for targeted drug delivery -- inspired by Russian pelmeni

 E-Mail An international team led by a Skoltech researcher has developed a method of fabrication for biodegradable polymer microcapsules, made more efficient by turning to an unusual source of inspiration - traditional Russian dumpling, or pelmeni, making. The two papers were published in Materials and Design and ACS Applied Materials and Interfaces. Micro-sized capsules, which can be tailored to a variety of purposes, have proven very useful in targeted delivery of drugs and other bioactive compounds. To ensure optimal functioning, these have to be designed and manufactured with precision and in particular shapes, as non-spherical capsules turned out to be more efficient and effective than spherical ones.

Biodegradable microcapsules guide neuronal development

Biodegradable microcapsules guide neuronal development
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Biodegradable microcapsules guide neuronal development by delivering nerve growth factor

Biodegradable microcapsules guide neuronal development by delivering nerve growth factor ANI | Updated: Feb 21, 2021 17:36 IST Moscow [Russia], February 21 (ANI): Researchers from Skoltech and their colleagues have demonstrated that nanoengineered biodegradable microcapsules can guide the development of hippocampal neurons in an in-vitro experiment. These microcapsules play a critical role in nerve growth factor, a peptide that is necessary for neuron growth. The findings of the study were published in the journal Pharmaceutics. Many neurodegenerative conditions that can lead to severe disorders are associated with depleted levels of growth factors in the brain - neuropeptides that help neurons grow, proliferate and survive. Some clinical studies of Alzheimer s and Parkinson s diseases have shown that delivering these growth factors to specific degenerating neurons can have a therapeutic effect.

Микрокапсулы Сколтеха помогут при лечении болезней Альцгеймера и Паркинсона

Микрокапсулы Сколтеха помогут при лечении болезней Альцгеймера и Паркинсона
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