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Travere Therapeutics to Present Abstracts at the American Society of Nephrology (ASN) Kidney Week 2023

Travere Therapeutics to Present Abstracts at the American Society of Nephrology (ASN) Kidney Week 2023
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Travere Therapeutics to Present Abstracts at the American Society of Nephrology (ASN) Kidney Week 2023

Travere Therapeutics to Present Abstracts at the American Society of Nephrology (ASN) Kidney Week 2023
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18 Share Tips | 26th June 2023

Delta4 Identifies a Potential New Therapeutic Option for Focal Segmental Glomerulosclerosis (FSGS) using computational Hyper-C Drug Discovery Platform

/PRNewswire/ Delta4, a pioneering digital drug discovery company specializing in identifying new therapeutic indications for drugs with established safety.

Inaxaplin reduces proteinuria in focal segmental glomerulosclerosis with two APOL1 variants

1. In preclinical studies, inaxaplin selectively inhibited apolipoprotein L1 (APOL1) in vitro and reduced proteinuria in a APOL1 G2-homologous transgenic mouse model of proteinuric kidney disease. 2. In a following phase 2a clinical study, 13 participants treated with inaxaplin had a significant reduction in urinary protein-to-creatinine ratio at week 13. Evidence Rating Level: 3 (Average)

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