A new study assesses the effect of the gremlin-1 (GREM1) protein on the in vitro and in vivo stability of bone marrow stem cell (BMSC)-derived cartilage engineered within scaffolds.
A new dual delivery system designed to sequentially release BMP2 and IGF1 in microparticles in an injectable hydrogel successfully healed an 8-mm cranial defect in rats.
A new study compares the regenerative potential of blood/bone marrow aspirate concentrates obtained from arterial blood, venous blood, and bone marrow aspirate. The study, conducted in rabbits, is reported in the peer-reviewed journal Tissue Engineering Part A.
Regenerative Potential of Solid Bone Marrow Aspirate Concentrate miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Gelatin hydrogel can be used in trophoblast spheroid motility assays, shows study
Trophoblast cells, which surround the developing blastocyst in early pregnancy, play an important role in implantation in the uterine wall. A new multidimensional model of trophoblast motility that utilizes a functionalized hydrogel is described in the peer-reviewed journal
Tissue Engineering, Part A.
This valuable new tool, based on a methacrylamide-functionalized gelatin hydrogel, can be used for three-dimensional trophoblast spheroid motility assays. It can resolve quantifiable differences in outgrowth area and viability in the presence of a known invasion promoter and a known invasion inhibitor.
Implantation involves a highly coordinated molecular dialogue between endometrial cells and trophoblast cells. Developing a deeper understanding of the biological mechanisms surrounding implantation may provide critical insights into pregnancy and pregnancy disorders.