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Telomere Shortening And Ageing

Telomeres are cap- like structures at chromosome ends that play an important role in ageing and in the initiation and progression of various diseases.

Biological ageingDna repairEll deathMyelodysplastic syndromeEmatopoietic stem cell disorder

Synthetic human embryos let researchers study early development while sidestepping ethical and logistical hurdles

Early human development is a complex, multistep process that’s even more complicated to study in the lab. Models made from stem cells avoid some of the trouble with using real human embryos.

International society for stem cell researchInternational societyStem cell researchDevelopmental biologyGenetic engineeringHuman developmentHuman embryo researchHuman embryosOdel embryosReproductive biologySynthetic embryos

Study reveals how maternal diabetes affects birth defects at the single-cell level

The mechanisms by which maternal diabetes mellitus contributes to congenital abnormalities in the fetus.

United statesNature cardiovascular researchCell rangerBirth defectsDiabetes mellitusOxidative stressRetinoic acid

New AI approach captures the tempo and stages of embryonic development

Animal embryos go through a series of characteristic developmental stages on their journey from a fertilized egg cell to a functional organism.

University of konstanzNature methodsTwin networkTwin network basedEmbryonic developmentArtificial intelligenceDeep learning

Human post-implantation embryo models show promise in unraveling early development

Researchers evaluate post-implantation development in humans using embryo-like models based on genetically unmodified human naïve embryonic stem cells.

Marko aliaksandrN vitroEmbryonic stem cellsHuman embryosIn uteroN vivoStem cells

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