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Four Penn students are 2023 Goldwater Scholars

Benefits of endurance exercise in primary mitochondrial disease depend on the underlying mutation

Benefits of Exercise May Vary Greatly in Primary Mitochondrial Disease

Benefits of exercise may vary greatly in primary mitochondrial disease

Benefits of exercise may vary greatly in primary mitochondrial disease
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Mitochondrial Dysfunction May Raise Schizophrenia Risk in 22q Patients

Mitochondrial Dysfunction May Raise Schizophrenia Risk in 22q Patients A disorder called 22q11.2 deletion syndrome (22q) affects about one in 2,000 births, and causes dysfunction in every organ system including the heart and brain. It s been linked to behavioral changes including autism spectrum disorder, anxiety, and attention deficit hyperactive disorder. These problems may begin in adolescence and can persist in adults, when other psychiatric illnesses may emerge. Schizophrenia, for example, is about 25 times more likely in 22q patients. Researchers have now learned more about a connection between an organelle known as the powerhouse of cells, the mitochondria, and the development of schizophrenia in 22q patients. The findings, which were reported in

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