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Optimizing Afatinib Use: Dosing Strategies and Adverse Event Management

Explore dosing nuances and adverse event management strategies for afatinib in treating EGFR mutant non-small cell lung cancer, reflecting real-world practices and clinical insights.

Incyte to Spotlight More Than 40 Hematology and Oncology Abstracts Including a Plenary Presentation at the ASH Annual Meeting

Jazz Pharmaceuticals to Present Latest Advancements in Sleep Medicine at World Sleep 2023

Transcripts for CNN The Lead With Jake Tapper 20220207 22:21:00

response? when we first started designing the dosing strategies, 18 months ago. some of it was a guess. and also, when we started rolling out these vaccines, there was an urgency to get effective maybe response in the community which is why they space the pfizer vaccine at three weeks and moderna vaccine in four weeks. but it turns out, there is data to suggest you can get a more robust response if you wait a little bit longer for the second dose. the other potential benefit is that it is also thought that potentially, maybe most importantly, in younger people. that some of the side effects, the most worrisome would be myocarditis, might be lessoned if you gave the second dose spaced out maybe a month later. so it is an interesting strategy. it might make sense going forward to improve the immune

Transcripts for MSNBC Hallie Jackson Reports 20210823 14:18:00

expanded. but remember, the process while very, very rigorous for adults is even more so when it comes to children as it should be. remember, there are a number of different approaches to studying the vaccine in children. there s de-escalation, meaning you re going down in age and waiting for the 5 to 11 group. there s different dosing strategies making sure they re giving the kids the minimum amount of vaccine that s sufficient to produce the immune response. to specifically answer your question we are hoping to get that really important safety and effectiveness data this fall, meaning as early as, you know, next month in september, and then of course applying for the expansion to the authorization, it will take a number of months before the fda approves and then they ll determine who should be administered it. i remember it took two or three weeks before we saw the first approval. yeah.

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