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Depression may be associated with reduced adherence to direct-acting oral anticoagulants in atrial fibrillation patients

1. In this cross-sectional study, the odds of adequate or optimal adherence to direct-acting oral anticoagulants were lower in atrial fibrillation (AF) patients with depression than those without. 2. However, AF patients with depression demonstrated no difference in adherence to warfarin compared to those without. Evidence Rating Level: 3 (Average) Depression is a highly prevalent

Wellness Check: Mental Health | 2 Minute Medicine

Internet gaming disorders may be associated with insomnia, paranoid ideation, and psychoticism 1. In this cross-sectional study, a higher internet gaming disorder (IGD) score was associated with increasing insomnia severity, paranoid ideation, and psychoticism. 2. However, insomnia severity fully mediated the association between IGDs and paranoid ideation, while cyberbullying partially mediated the association between IGDs

Indefinite anticoagulation for unprovoked venous thromboembolism is not cost-effective

1. In this Markov modeling study, indefinite anticoagulation for first unprovoked venous thromboembolism (VTE) cost $16,014 more per person than discontinuation based on clinical guidelines. 2. Indefinite anticoagulation for first unprovoked VTE did not increase the number of quality-adjusted life-years (QALYs) per patient. Evidence Rating Level: 1 (Excellent) Study Rundown: VTE is estimated to have a

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