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Study Indicates Immune Molecule May Play Key Role In The Progression Of ALS

Study Indicates Immune Molecule May Play Key Role In The Progression Of ALS
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Targeting brain s immune cells may help prevent or treat Alzheimer s

A gene mutation linked to Alzheimer’s disease alters a signaling pathway in certain immune cells of individuals with the disease, according to a new

Lewy Body Dementia Center Without Walls - Discovery and Translation Labs: Brain Research

Advancing research on a common form of dementia Mayo Clinic researchers have assembled a team of international experts to investigate key proteins involved in Lewy body dementia. Lewy Body Dementia Center Without Walls Investigators from Mayo Clinic s Florida campus are leading a Lewy Body Dementia Center Without Walls research initiative funded by a National Institutes of Health (NIH) specialized center-cooperative agreement grant (U54). The overall goal of the Lewy body dementia multi-institutional Center Without Walls (CWOW) initiative is to deepen the understanding of how the Alzheimer s disease-related protein, amyloid-beta, and the Parkinson s disease-related protein, alpha-synuclein, interact to affect symptom presentation, disease progression and the underlying disease process in Lewy body dementia (LBD).

Mayo Clinic Brain Bank - Mayo Clinic Research

Mayo Clinic Brain Bank Mayo Clinic Brain Bank Neuroscientists at Mayo Clinic s campus in Florida are leaders in the discovery of new genes, biomarkers and therapeutic targets for brain diseases. Thanks to exceptional resources, including a brain bank for neurodegenerative disorders housed within Dr. Dickson s Neuropathology and Microscopy Laboratory, Mayo investigators continue to shed new light on the underlying causes of Alzheimer s disease, Parkinson s disease, amyotrophic lateral sclerosis (ALS), frontotemporal dementia and stroke. Dennis W. Dickson, M.D., the Robert E. Jacoby Professor of Alzheimer s Research, is a member of the Department of Neuroscience. He is past president of the American Association of Neuropathologists and a Potamkin Prize winner. He directs the brain bank with the assistance of a dedicated staff of brain bank coordinators, neurohistology technical staff and professional support staff. The brain bank, which continues to grow, currently houses more than

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