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Atlas Reveals Alzheimer s Impact on Brain Blood Vessels

Atlas Reveals Alzheimer s Impact on Brain Blood Vessels
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Atlas of human brain blood vessels highlights changes in Alzheimer s disease | MIT News | Massachusetts Institute of Technology

Atlas of human brain blood vessels highlights changes in Alzheimer s disease | MIT News | Massachusetts Institute of Technology
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Alzheimer s risk gene undermines insulation of brain s wiring | MIT News | Massachusetts Institute of Technology

MIT research shows that in people carrying the APOE4 risk variant, a key brain cell type mismanages cholesterol needed to insulate neurons properly another sign that APOE4 contributes to Alzheimer's disease by disrupting lipids in the brain.

Alzheimer s Risk Gene Undermines Insulation of Brain s Wiring

When people carry the Alzheimer's associated APOE4 gene, oligodendrocytes fail to transport fatty molecules to wrap neurons that make brain circuitry connections. This deficit of myelin may contribute to the pathology and symptoms of Alzheimer's disease.

Alzheimer s risk gene undermines insulation of brain s wiring

Alzheimer s risk gene undermines insulation of brain s wiring
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