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Astrazeneca Covid vaccine Q&A: What we know about blood clots, side effects and risks for under-30s

The UK medicines regulator says the benefits of the AstraZeneca vaccine continue to outweigh any risks 9 April 2021 • 4:19pm The UK medicines regulator has said the benefits of the Oxford/AstraZeneca vaccine continue to outweigh any risks, but under-30s will be offered an alternative jab. Meanwhile, in a separate update on its investigations on Wednesday, the European medicines watchdog has ruled that unusual blood clots were very rare side effects of the jab. Scientists have also insisted that further research is needed to understand more about the risk of these rare blood clots. On April 8, Health Secretary Matt Hancock reiterated that the vaccines currently in use in the UK, including the newly available Moderna vaccine, remained safe . 

Anticoagulation should not be regarded as primary cause of intracerebral haemorrhages, finds study

Anticoagulation should not be regarded as primary cause of intracerebral haemorrhages, finds study Cardiovascular diseases are usually complex and affect multiple organs simultaneously. Treatments for vascular diseases in the brain may therefore have implications for the treatment of cardiac diseases. It is therefore important to understand the respective causes and effects. This study explores the causes of intracerebral haemorrhages and links them to the risk of stroke associated with atrial fibrillation. It suggests a fundamental new assessment of the effects of blood thinning on intracerebral haemorrhages. About 1,000 patients with intracerebral haemorrhage are treated at stroke units each year in Switzerland. Intracerebral haemorrhages are more often fatal than other forms of strokes, and their incidence has not decreased in the past 30 years. The use of blood thinners was previously considered not only to be a risk factor but potential cause for a intracerebral haemorrhage.

Astrazeneca Covid vaccine Q&A: What we know about blood clots, side effects and risks for under-30s

The UK medicines regulator has said the benefits of the Oxford/AstraZeneca vaccine continue to outweigh any risks, but under-30s will be offered an alternative jab. Meanwhile, in a separate update on its investigations on Wednesday, the European medicines watchdog has ruled that unusual blood clots were very rare side effects of the jab. Some European countries have restricted the vaccine for younger people following reports of cerebral venous sinus thrombosis (CVST), a specific type of clot that prevents blood from draining from the brain, as well as low platelet counts - cells that help blood clot. Prime Minister Boris Johnson has said people should follow the regulator s advice and keep getting their jabs.

European Medicines Agency Official: Clear Link Between AstraZeneca Vaccine and Blood Clots in the Brain

European Medicines Agency Official: “Clear Link” Between AstraZeneca Vaccine and Blood Clots in the Brain The UK has paused a trial on children while the clots are investigated Image Credit: Share Email An official with the European Medicines Agency said Tuesday that there is a “clear link” between the AstraZeneca vaccine and deadly blood clots in the brain. Marco Cavaleri, the chair of the vaccine evaluation team at the EMA, told the Italian newspaper Il Messagero that in his opinion, “we can now say it is clear that there is an association (of the brain blood clots) with the vaccine.” Cavaleri added that while he was sure that there was a “clear link” with the AstraZeneca vaccine and blood clots, it is still not yet known what the actual cause of the deadly brain clots is.

Anticoagulation and cerebral small vessel disease

Credit: Insel Gruppe Cardiovascular diseases are usually complex and affect multiple organs simultaneously. Treatments for vascular diseases in the brain may therefore have implications for the treatment of cardiac diseases. It is therefore important to understand the respective causes and effects. This study explores the causes of intracerebral haemorrhages and links them to the risk of stroke associated with atrial fibrillation. It suggests a fundamental new assessment of the effects of blood thinning on intracerebral haemorrhages. About 1,000 patients with intracerebral haemorrhage are treated at stroke units each year in Switzerland. Intracerebral haemorrhages are more often fatal than other forms of strokes, and their incidence has not decreased in the past 30 years. The use of blood thinners was previously considered not only to be a risk factor but potential cause for a intracerebral haemorrhage.

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