Objective
The objective of this study is to investigate the regional homogeneity (ReHo) of spontaneous brain activities in Parkinson’s disease (PD) patients.
Methods
In total, 20 PD patients and 20 matched normal controls (NCs) participants were recruited for this study. The regional homogeneity (ReHo) approach based on resting-state functional magnetic resonance imaging on a 3T MRI system was used to investigate local brain activity. We examined activity in two frequency bands, slow‐4 (0.027-0.073 Hz) and slow‐5 (0.010-0.027 Hz). Two-sample t-tests were used to determine the between-group differences in the ReHo data. Pearson correlation analysis was used to explore the relationships between the ReHo values and clinical indices in PD patients.
Results
Compared with NCs, PD patients showed decreased ReHo values in the right middle occipital gyrus, right cuneus, and left superior occipital gyrus, and increased ReHo values in the right middle frontal gyr
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