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Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

Zachary Schug, Ph.D., assistant professor in the Molecular and Cellular Oncogenesis Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute, has published a new paper in the journal Nature Cancer.

Zachary schugLily ramseyWistar instituteRonald caplan cancer centerCellular oncogenesis program of the ellenCellular oncogenesis programAssistant professorBreast cancerGrowth factorImmune systemT cell

Wistar Researchers Discover Possible New Treatment for Triple-Negative Breast Cancer

Wistar Researchers Discover Possible New Treatment for Triple-Negative Breast Cancer
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United statesUniversity of pennsylvaniaAndrew kossenkovRahuls shindeMichael hulseSara pappJosephm salvinoKathryne wellenToshitha kannanYellamellivv srikanthGauri mirjiSteven zhaoWistar proteomicKatherinea pniewskiDanielt claiborneKatelynd miller

Researchers discover possible new treatment for triple-negative breast cancer

Researchers discover possible new treatment for triple-negative breast cancer
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Katelynd millerZachary schugRonald caplan cancer centerWistar instituteCellular oncogenesis program of the ellenCellular oncogenesis programNature cancer

Wistar researchers discover possible new trea

Zachary Schug, Ph.D., assistant professor at The Wistar Institute, has published a new paper in the journal Nature Cancer demonstrates a double-acting mechanism for fighting a particularly aggressive, difficult-to-treat form of breast cancer. Schug’s research shows how silencing a certain gene, ACSS2, may improve existing treatments for patients.

United statesUniversity of pennsylvaniaToshitha kannanJosephm salvinoWistar proteomicGauri mirjiSeamus oconnorKatelynd millerKathryne wellenZachary schugSteven zhaoSusang komenReyes acostaYellamellivv srikanthRahuls shindeAndrew kossenkov

Wistar scientists uncover a key mechanism as to how p53 suppresses tumors

The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it.

United statesNoam auslanderEmily hendersonMaureene murphyAmerican association for cancer researchRonald caplan cancer centerWistar instituteMolecular cellular oncogenesis programCancer discoveryAmerican associationCancer researchAfrican americansIra brind professorCellular oncogenesis programAshkenazi jewishMolecular screening