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Wistar scientists uncover a key mechanism as to how p53 suppresses tumors

Wistar Scientists Discover Innate Tumor Suppression Mechanism

Wistar Scientists Discover Innate Tumor Suppression Mechanism
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Newly identified gene signature helps assess cancer risk and optimize treatment

In a paper published in PNAS, Maureen Murphy, Ph.D., Deputy Director of Wistar's Ellen and Ronald Caplan Cancer Center and Ira Brind Professor and Program Leader in the Molecular & Cellular Oncogenesis Program, and team have identified a gene signature that accurately predicts the functioning of P53 variants, important information to assessing cancer risk and optimizing choices for cancer therapeutics.

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