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The GPCR Puzzle: New Research Reveals Molecular Origins of Function for a Key Drug Target

Scientists at St. Jude Children's Research Hospital, collaborating internationally, used data science, pharmacology, and structural details to explore at the atomic level how each amino acid in the adrenaline-binding receptor affects its activity when interacting with this natural ligand. They di

UofT Researchers AI Crafts Proteins for Gene Therapy

UofT Researchers AI Crafts Proteins for Gene Therapy
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St Jude researchers crack the code of the β2-adrenergic receptor

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

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