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Lisata Therapeutics, Inc (NASDAQ:LSTA) Q1 2024 Earnings Call Transcript

Lisata Therapeutics, Inc (NASDAQ:LSTA) Q1 2024 Earnings Call Transcript
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United statesNew south walesNew zealandJohn mendittoRobert leboyerPete enderlinErkki ruoslahtiDavid mazzoJames niscoRobert sassoonJoseph pantginisSteve brozakSara nikTherapeutic goods administrationClinical trial centerTherapeutic goods regulatory agency of the australian

Caladrius Biosciences (CLBS) to Merge with Cend Therapeutics

Caladrius Biosciences (CLBS) to Merge with Cend Therapeutics
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Davidj mazzoDavid slackCaladrius biosciences incEuropean society for molecular oncologyCend therapeutics incLisata therapeutics incCend therapeuticsLisata therapeuticsCendr platformC end ruleMolecular oncologyChief executive officerChief business officerExecutive vice presidentChief medical officer

Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

A study recently identified Neurolipin-1 or NRP1, a host factor for SARS-CoV-2 infection, as a cargo retrograde-transported by the ESCPE-1.

Retrograde endosomal sortingImage creditC end ruleCoronavirus disease covid 19Ars cov 2Hela cellsEvere acute respiratoryEvere acute respiratory syndrome

[Full text] tLyP-1 Peptide Functionalized Human H Chain Ferritin for Targeted Deli

Cellular Uptake The cellular uptake properties of the proteins labeled with FITC were analyzed by flow cytometry. The uptake of HFtn by tumor cells was mediated by TfR1 has been proved previously. As shown in Figure 3, cellular uptake of HFtn was much higher than that of free FITC, which is probably attributed to the TfR1 receptor-mediated endocytosis. Significantly, the mean fluorescence intensity of FITC-tLyP-1-HFtn was approximately three-fold higher than FITC-HFtn, suggesting that the enhanced intracellular uptake of tLyP-1-HFtn was probably attributed to TfR1 and NRP-1 dual receptor-mediated endocytosis. In contrast, FITC-M-tLyP-1-HFtn showed similar mean fluorescence intensity as the FITC-HFtn, indicating that the mutation at the tLyP-1 peptide sequence resulted in the inactivation of the NRP-1 receptor-mediated endocytosis.

United statesZhejiang tianhang biotechnology co ltdBiosharp life sciencesCo ltdLaboratory animal coChinese academy of sciences shanghaiEnergy chemical shanghaiTransgen biotech co ltdShanghai yuanye biotechnology co ltdGuangzhou saiguo biotech co ltdGe healthcareC end ruleTakara biotechEnergy chemicalBeyotime biotechnologyBiosharp life