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#VisualAbstract: Early endovascular thrombectomy improves functional outcomes in large infarct ischaemic stroke

1. Patients in the thrombectomy group reported significantly greater improvement, with lower mortality at 90 days versus medical management alone. 2. Symptomatic intracranial hemorrhage was comparable between groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Patients with acute ischemic stroke and large vessel infarct benefit from endovascular thrombectomy. However, previous studies have shown clinical benefits using

Minute medicine incRating levelRankin scaleEndovascular thrombectomyLarge ischemicBetween julIschemic strokeLarge stroke

Early endovascular thrombectomy improves functional outcomes in large infarct ischaemic stroke

1. Patients in the thrombectomy group reported significantly greater improvement, with lower mortality at 90 days versus medical management alone. 2. Symptomatic intracranial hemorrhage was comparable between groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Patients with acute ischemic stroke and large vessel infarct benefit from endovascular thrombectomy. However, previous studies have shown clinical benefits

Rating levelRankin scaleEndovascular thrombectomyLarge ischemicBetween julAcute ischemic strokeIschemic strokeMechanical thrombectomyChronic disease

Atezolizumab added to cabozantinib does not improve clinical outcomes in patients with metastatic renal cell carcinoma

1. Progression-free and overall survival was comparable in both the intervention and control groups. 2. Serious adverse events were more common among patients taking a combination of atezolizumab-cabozantinib than cabozantinib-only. Evidence Rating Level: 1 (Excellent) Study Rundown: Immune checkpoint inhibitors are first-line therapy for patients with metastatic renal cell carcinoma (MRCC); however, optimal management for

Rating levelAdvanced renal cellBetween julImmune checkpoint inhibitorsKidney cancerMetastatic renal cell carcinomaRenal cell carcinomaVegf inhibitorsChronic disease

#VisualAbstract: Best endovascular treatment superior to vein bypass for patients with chronic limb ischemia requiring infrapopliteal revascularization

1. Major amputation and all-cause mortality were higher in the vein bypass group compared to the best endovascular treatment group. 2. Cardiovascular and respiratory-related events contributed to most morbidity and mortality cases. Evidence Rating Level: 1 (Excellent) Study Rundown: Chronic limb ischemia is the most severe form of peripheral arterial disease which often requires

United kingdomBetween jul

Best endovascular treatment superior to vein bypass for patients with chronic limb ischemia requiring infrapopliteal revascularization

1. Major amputation and all-cause mortality were higher in the vein bypass group compared to the best endovascular treatment group. 2. Cardiovascular and respiratory-related events contributed to most morbidity and mortality cases. Evidence Rating Level: 1 (Excellent) Study Rundown: Chronic limb ischemia is the most severe form of peripheral arterial disease which often requires invasive

United kingdomRating levelTranscatheter arterializationDeep veinsChronic limb threateningBetween julPeripheral arterial diseasePeripheral vascular diseaseVascular surgeryVein bypassChronic disease

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