1. In this randomized-controlled trial, two 12-day courses of teplizumab improved C-peptide levels compared to placebo at week 78 in patients with stage three type 1 diabetes. 2. No significant differences were observed between the teplizumab and placebo groups with respect to secondary clinical outcomes, including clinically relevant hypoglycemic events. Evidence Rating Level: 1 (Excellent) Study
Dr. Akshat Chadha, a Lifestyle Doctor at GOQii, emphasizes the importance of a balanced approach to reversing diabetes. While some individuals with prediabetes may achieve long-term reversal through lifestyle changes, those with chronic diabetes may find it challenging to sustain reduced medications. Extreme diets can lead to temporary improvements in blood reports and weight loss but may result in chronic deficiencies and other health issues. Instead, focusing on balanced meals and incorporating fasting under proper guidance can improve blood sugars and overall health. While family history plays a role in diabetes predisposition, lifestyle habits are significant factors. Early medication or insulin use may help preserve beta-cell function. Taking responsibility for one's health is essential, along with trusting medical advice.
Benefits of the blood pressure drug verapamil include delayed type 1 diabetes progression, lowered insulin requirements and preservation of beta cell function.