Pregnancies resulting in miscarriage between 2004 and 2018 were included in the case group and matched in a 1:1 ratio with control individuals. The study, published in the journal JAMA Psychiatry, included 3,067,122 (over 30 lakh) pregnancies among 1,957,601 (over 19 lakh) women. It was found that 4.4 per cent of these pregnancies resulted in miscarriage.
A meta-analysis of studies found that the risk of dementia increased 22% for every additional twenty daily doses of benzodiazepine medications annually.
Despite the well-known risks of the drugs, especially for the elderly, prescription use of addictive benzodiazepine sedatives in the United States increases steadily with age, according to a large-scale study published in JAMA Psychiatry. Overall, as of 2008, 5.2% of American adults were taking the drugs. The study also showed that women were twice as likely to be taking benzodiazepines as men. National Institute of Mental Health director Thomas Insel called the findings "worrisome."