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The Y Chromosome Is Going To Disappear, Scientists Say

"The human Y is in the very last stages of degeneration, and the big question is how long till it, too, gets lost," expert Jenny Graves told Newsweek.

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Y chromosomes can disappear as men age, causing deadly conditions

The entire Y chromosome can disappear from cells as they divide if DNA replication has enough errors, leading to the mLOY defect.

Osaka metropolitan universityAy chromosome

Y chromosome loss from immune cells may cause heart disease

The Y chromosome, involved in sex determination, mysteriously disappears from some men’s immune cells as they get older – and that could be fatal

Clare wilsonAy chromosomeHeart diseaseOsaic loss of chromosome yImmune cellsHeart failure

Is There a Link Between Heart Failure and Y Chromosome in Men?

Yes. There is a link between the mosaic loss of Y chromosome and heart failure of aging men as revealed by a study and it has been successfully done in mice.

United kingdomHeart failureAy chromosomeOsaic loss ofy chromosomeRaging menHematopoietic cells

Y chromosome loss through aging can lead to an increased risk of heart failure and death from cardiovascular disease, new research finds

The negative health effects of Y chromosome loss could be one potential reason women tend to live longer than men.

Research briefAge related declineCardiovascular diseaseHeart diseaseHeart failureNew researchUick readsResearch briefSex chromosomesK biobankAy chromosomeAge related disease

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