Updated Feb 01, 2021 | 10:38 IST
The team examined the prognostic significance of the expression of meflin and gremlin 1 (two types of proteins) in colorectal cancer patients. Scientists find a way to stop colorectal cancer progression: 5 things you can do to prevent the disease | Photo Credit: iStock Images
Key Highlights
Previous studies have shown that the proliferation of fibroblasts is largely involved in the progression of colorectal cancer
Colorectal cancer happens when abnormal cells grow in the lining of the colon or the rectum
Here s what you can do today to prevent or reduce your risk of developing colorectal cancer
New Delhi: Scientists from Japan may have found a way to curb the spread of colorectal cancer tumours, a finding that may help develop an effective strategy for preventing the disease progression. Colorectal cancer is a type of cancer that begins in the colon (large intestine) or rectum. In a new study, Nagoya Univers
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Nagoya University researchers and colleagues have revealed that colorectal cancer tissues contain at least two types of fibroblasts, namely, cancer-promoting fibroblasts and cancer-restraining fibroblasts, and that the balance between them is largely involved in the progression of colorectal cancer. Their findings suggest that artificially altering the balance between the two types of cells could curb the spread of colorectal cancer tumors, which may become an effective strategy for preventing cancer progression.
Nagoya University researchers and colleagues have revealed that colorectal cancer tissues contain at least two types of fibroblasts (a type of cells found in connective tissue), namely, cancer-promoting fibroblasts and cancer-restraining fibroblasts, and that the balance between them is largely involved in the progression of colorectal cancer.
Study discovers expected restorative targets can repress colorectal cancer progression ANI | Updated: Jan 31, 2021 01:48 IST
Nagoya [Japan], January 31 (ANI): Scientists from Nagoya University have found that colorectal cancer tissues contain two kinds of fibroblasts (a sort of cells found in connective tissue), namely those that promote and restrain cancer that the harmony between them is generally engaged with the spread of the disease.
Their findings, published in the journal Gastroenterology, suggest that Artificially altering the balance between the two types of cells could curb the spread of colorectal cancer tumors, which may become an effective strategy for preventing cancer progression.
Cancer tissues comprise both cancer cells and non-malignant cells such as fibroblasts. Previous studies have suggested that the proliferation of fibroblasts is largely involved in the progression of colorectal cancer, the most common cancer in Japan.