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Understanding how Cas9 binds off-target sequences can help researchers refine CRISPR-mediated genome editing.

City ofUnited kingdomShengdar tsaiMatt newtonAshleigh campsallDavid ruedaFrancis crick instituteJude children research hospitalImperial college londonMolecular cellImperial collegeStar trekJude childrenResearch hospitalStruct molNatl acad