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BC Platforms, Euformatics and Oncompass Medicine form a partnership to develop oncology NGS workflows for buyer consortium of seven major European hospitals

Blood test detects childhood tumors based on their epigenetic profiles

Credit: Tatjana Hirschmugl A new study exploits the characteristic epigenetic signatures of childhood tumors to detect, classify and monitor the disease. The scientists analyzed short fragments of tumor DNA that are circulating in the blood. These liquid biopsy analyses exploit the unique epigenetic landscape of bone tumors and do not depend on any genetic alterations, which are rare in childhood cancers. This approach promises to improve personalized diagnostics and, possibly, future therapies of childhood tumors such as Ewing sarcoma. The study has been published in Nature Communications. A study led by scientists from St. Anna Children s Cancer Research Institute (St. Anna CCRI) in collaboration with CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences provides an innovative method for liquid biopsy analysis of childhood tumors. This method exploits the fragmentation patterns of the small DNA fragments that tumors leak into the blood stream, whi

ALSF announces grant award recipients of Crazy 8 Initiative in pediatric oncology

ALSF announces grant award recipients of Crazy 8 Initiative in pediatric oncology Alex s Lemonade Stand Foundation (ALSF), a nonprofit foundation devoted to finding cures for all children with cancer, announces grant award recipients of their Crazy 8 Initiative. The recipients will receive grants totaling more than $18.5 million, which is the single, largest funding commitment from ALSF to date. The Initiative kicked off in the Fall of 2018 with a meeting that brought together more than 90 scientists from around the world to help define the research landscape in eight key areas of need in order to tackle major obstacles impeding progress toward cures for childhood cancer. Through a rigorous review process, ALSF received over 100 letters of intent from researchers that resulted in 83 full grant applications which were ultimately narrowed down to four projects that will work to accelerate the pace of new cure discovery.

Alex s Lemonade Stand Foundation Awards More Than $18 5 Million to Recipients of Crazy 8 Initiative to Advance Pediatric Cancer Research

Share this article Share this article PHILADELPHIA, March 17, 2021 /PRNewswire/  Alex s Lemonade Stand Foundation (ALSF), a nonprofit foundation devoted to finding cures for children with cancer, announces grant award recipients of their Crazy 8 Initiative. The recipients will receive grants totaling more than $18.5 million, which is the single, largest funding commitment from ALSF to date. The Initiative kicked off in the Fall of 2018 with a meeting that brought together more than 90 scientists from around the world to help define the research landscape in order to tackle major obstacles impeding progress toward cures for childhood cancer. Through a rigorous review process, ALSF narrowed down over 100 applications to four projects that will work to accelerate the pace of new cure discovery.

Alex s Lemonade Stand Foundation Gives $18 5M, Largest Amount Yet

Alex s Lemonade Stand Foundation Gives $18 5M, Largest Amount Yet
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