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Dynamic mapping of the cell-generated force of cardiomyocytes will help provide an intrinsic understanding of the heart. However, a real-time, dynamic, and high-resolution mapping of the force distribution across a single living cell remains a challenge. Here, we established a force mapping method based on a “light nano-antenna” array with the use of piezo-phototronic effect. A spatial resolution of 800 nm and a temporal resolution of 333 ms have been demonstrated for force mapping. The dynamic mapping of cell force of live cardiomyocytes was directly derived by locating the antennas’ positions and quantifying the light intensities of the piezo-phototronic light nano-antenna array. This study presents a rapid and ultrahigh-resolution methodology for the fundamental study of cardiomyocyte behavior at the cell or subcellular level. It can provide valuable information about disease detection, drug screening, and tissue engineering for heart-related studies.
This year between January and March in 2021, the Pastures for Profit curriculum will be offered as a virtual course. One live webinar will be offered per month along with “work at your own pace” videos and exercises that accompany each webinar. The Pastures for Profit program is a collaboration between Ohio State University Extension, Central State University, USDA-Natural Resources Conservation Service, Ohio Federation of Soil and Water Conservation Districts, Ohio Department of Agriculture, and the Ohio Forage and Grasslands Council.
Each webinar will be offered live on Zoom at 7 P.M. and feature three presentations in a 90-minute span. Attendees will be able to interact with the speakers and ask questions in real time. Once registered, attendees will be granted access to the online course including the webinars and complementary resources. Participants that attend all three webinars will have the opportunity to earn a certificate of completion. Registered participants will al