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Researchers find new subtypes for ovarian cancer

New research findings based on the evolution of malignant tumours increase our understanding of the characteristics of an ovarian cancer subtype that is difficult to treat. The findings may also make it easier to effectively target therapies at the right patients.

Difficult-to-treat ovarian cancer has new subtypes

Difficult-to-treat ovarian cancer has new subtypes
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Research findings bring order to the genomic chaos of ovarian high grade serous carcinoma

A sleep disorder associated with shift work may affect gene function

Date Time A sleep disorder associated with shift work may affect gene function Going on holiday can affect shift workers on the level of gene function: a new study indicates that resting during a holiday period restored functions associated with DNA regulation in shift workers suffering from sleep deprivation. Long-term sleep deprivation is detrimental to health, increasing the risk of psychiatric and somatic disorders, such as depression and cardiovascular diseases. And yet, little is known about the molecular biological mechanisms set in motion by sleep deprivation which underlie related adverse health effects. In a recently published study, the University of Helsinki, the Finnish Institute for Health and Welfare, the Finnish Institute of Occupational Health and the Finnair airline investigated dynamic changes to DNA methylation in shift workers. DNA methylation denotes epigenetic regulation that modifies gene function and regulates gene activity without changing t

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