Long-term opioid use increases the risk of abuse and overdose in this population. The study was published as a preprint and has not yet been peer reviewed.
Two new studies report results with adjuvant chemotherapy in older patients with stage 3 colorectal cancer; those who can tolerate it have better outcomes.
Follow-up that was provided in a general practice led to similar rates of detection of recurrences, and there was no difference in mortality compared to care provided by a surgeon.
Cell-free DNA concentration is significantly increased in the first 2 weeks after surgery but these higher levels do not seem to interfere with monitoring of circulating tumor DNA for prognostic purposes.
The agency expanded the indication for pembrolizumab to the adjuvant setting for patients with stage IB-IIIA NSCLC following surgery and platinum-based chemo.