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Over one in 3 rare childhood disorders diagnosed in 6 years

Credit: A STAR s Genome Institute of Singapore (GIS) 22 December 2020, Singapore - For over 20 years, the Genetics Service at the KK Women s and Children s Hospital (KKH) has been providing clinical care to patients with genetic disorders. In 2014, BRIDGES (Bringing Research Innovations for the Diagnosis of GEnetic diseases in Singapore) was set up, in collaboration with genomic research institutes at SingHealth, Agency for Science, Technology and Research (A STAR) and Duke-NUS to synergise the diagnostic efforts and patient outcome management. After six years, the KKH has met the goals set out in its BRIDGES programme, achieving 39 per cent in diagnostic yield through identifying more patients with genetic mutations. This result is on par with similar research programmes globally which have a diagnostic yield of 25 to 40 per cent.

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