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Scientists identify existing drugs that may inhibit SARS-CoV-2 virus The COVID-19 pandemic has caused more than 600,000 deaths in the United States since the start of 2020 and more than 4 million globally. The search for effective treatments against the disease are ongoing, and one hurdle is that SARS-CoV-2, the virus that causes COVID-19, has a number of tricks up its molecular sleeve when it comes to infecting people. In a recent study published in Nature Communications Biology, researchers from the U.S. Department of Energy s (DOE) Argonne National Laboratory and the University of Chicago identified a way to interfere with a sneaky mechanism the virus uses to prevent a response from an infected person s immune system.

United statesYoungchang kimNatalia maltsevaAndrzej joachimiakWilliam jorgensenKaren andersonEmily hendersonYale universityYale cancer centerNature communications biologyUs department of energyAmerican chemical societyOffice of science user facility at argonneArgonne national laboratoryUniversity of chicagoStructural biology center