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Existing drug may be effective in treating SARS-CoV-2

Existing drug may be effective in treating SARS-CoV-2 Scientists from the University of Chicago have found that the drug masitinib may be effective in treating COVID-19. The drug, which has undergone several clinical trials for human conditions but has not yet received approval to treat humans, inhibited the replication of SARS-CoV-2, the virus that causes COVID-19, in human cell cultures and in a mouse model, leading to much lower viral loads. X-ray crystallography gave us a strong indication of how this drug works, and we became confident that it has a chance to work in humans. Nir Drayman, University of Chicago

Masitinib Inhibits the Replication of SARS-CoV-2 in Preclinical Models

Masitinib Inhibits the Replication of SARS-CoV-2 in Preclinical Models
technologynetworks.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from technologynetworks.com Daily Mail and Mail on Sunday newspapers.

Existing drug is shown to inhibit SARS-CoV-2 virus

Existing drug is shown to inhibit SARS-CoV-2 virus
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Scientists deconstruct the protein-based machine responsible for SARS-CoV-2 replication

Scientists deconstruct the protein-based machine responsible for SARS-CoV-2 replication In February 2020, a trio of bio-imaging experts were sitting amiably around a dinner table at a scientific conference in Washington, D.C., when the conversation shifted to what was then a worrying viral epidemic in China. Without foreseeing the global disaster to come, they wondered aloud how they might contribute. Nearly a year and a half later, those three scientists and their many collaborators across three national laboratories have published a comprehensive study in Biophysical Journal that - alongside other recent, complementary studies of coronavirus proteins and genetics - represents the first step toward developing treatments for that viral infection, now seared into the global consciousness as COVID-19.

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