SARS-CoV-2 mAb cocktail effective against all known variants of virus
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A monoclonal antibody (mAb) cocktail, that targets sites on the Spike protein other than the E484K residue, can neutralise SARS-CoV-2.
A monoclonal antibody (mAb) cocktail to neutralise the COVID-19 virus developed at Vanderbilt University Medical Center (VUMC), US, is effective against all known strains, or variants, of the virus, according to researchers. The study was led by scientists at Washington University School of Medicine in St Louis, US.
In cell culture studies, the researchers determined the ability of mAbs, as well as antibodies isolated from the convalescent plasma of previously infected people, to neutralise highly transmissible variants of the SARS-CoV-2 virus that have arisen in the UK, South Africa, Brazil and elsewhere.