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Proof of concept for automated Fire Monkey High Molecular Weight (HMW) DNA extraction/size selection process in multi-well filter plate format validated by sequencing
Hands-free automated protocol on a bespoke Tecan Fluent 780 robotic liquid handler integrated with a Rotanda 460 robotic centrifuge
Extraction produces library-ready homogenous, long-length DNA (average 106kb) for short- and long-read DNA sequencing
Resultant sequence quality equivalent to manually-extracted DNA: >30Gb at N50 longer than 30kb
Automated DNA extraction enables further growth in high-throughput DNA sequencing applications with estimated market to >$50bn over the next 10 years
The UK genomic tools developer, RevoluGen Ltd. (RevoluGen or the Company), today announces the technology validation of the world's first automated extraction of library-ready High Molecular Weight (HMW) DNA in a multi-well filter plate format.