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First Automated System Using Fire Monkey HMW-DNA Extraction Installed at Quadram Institute for Pathogen Sequencing and AMR Monitoring

RevoluGen Ltd : First Automated System Using Fire Monkey HMW-DNA Extraction Installed at Quadram Institute for Pathogen Sequencing and AMR Monitoring

RevoluGen Ltd : RevoluGen s Automated Fire Monkey HMW-DNA Extraction Validated on Tecan Robot Supports Rapid Growth in Multiplexed DNA Sequencing

(2) Proof of concept for automated Fire Monkey High Molecular Weight (HMW) DNA extraction/size selection process in multi-well filter plate format validated by sequencing Hands-free automated protocol on a bespoke Tecan Fluent 780 robotic liquid handler integrated with a Rotanda 460 robotic centrifuge Extraction produces library-ready homogenous, long-length DNA (average 106kb) for short- and long-read DNA sequencing Resultant sequence quality equivalent to manually-extracted DNA: >30Gb at N50 longer than 30kb Automated DNA extraction enables further growth in high-throughput DNA sequencing applications with estimated market to >$50bn over the next 10 years The UK genomic tools developer, RevoluGen Ltd. (RevoluGen or the Company), today announces the technology validation of the world s first automated extraction of library-ready High Molecular Weight (HMW) DNA in a multi-well filter plate format.

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