Researchers characterize a novel gene likely to cause neurological disorders in humans

A multidisciplinary study led by Vanja Nagy (LBI-RUD/CeMM/MedUni Vienna) and Josef Penninger (UBC/IMBA) characterized a novel gene, known as FIBCD1, to be likely causative of a new and rare neurodevelopmental disorder. Using data from two young patients with neurological symptoms, the researchers from both groups found evidence of a novel function for the FIBCD1 gene in the brain, and a potentially pivotal role in diseases such as autism, ADHD, schizophrenia, and neurodegenerative disorders including Alzheimer's. The study makes an important contribution to the understanding of the extracellular matrix in the brain and its associated neurological diseases.

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United States ,China ,Austria ,United Kingdom ,British ,Austrian ,Josef Penninger ,Astrid Hagelkruys ,Vanja Nagy ,Emily Henderson ,Institute Of Molecular Biotechnology The Oe ,University Of British Columbia ,University Of Vienna Meduni ,Ludwig Boltzmann Institute Of Rare ,Cemm Research Center ,Meduni Vienna ,Ludwig Boltzmann Institute ,Undiagnosed Diseases ,Molecular Medicine ,Medical University ,British Columbia ,Molecular Biotechnology ,Christopher Fell ,Austrian Academy ,