When KFF Health News’ “What the Health?” podcast launched in 2017, Republicans in Washington were engaged in an (ultimately unsuccessful) campaign to “repeal and replace” the Affordable Care Act. The next six years would see a pandemic, increasingly unaffordable care, and a health care workforce experiencing unprecedented burnout. In the podcast’s 300th episode, host and chief Washington correspondent Julie Rovner explores the past and possible future of the U.S. health care system with three prominent “big thinkers” in health policy: Ezekiel Emanuel of the University of Pennsylvania, Jeff Goldsmith of Health Futures, and Farzad Mostashari of Aledade.