Dublin-listed pharmaceutical services company Open Orphan has announced that its subsidiary hVivo has signed a £3 million contract to develop a âchallenge virusâ based on new emerging variants of Covid-19.
The contract is with Imperial College London as part of a Wellcome Trust-funded initiative to manufacture a SARS-CoV-2 challenge virus.
Under the agreement, hVivo will develop a new SARS-CoV-2 challenge virus based on new emerging variants of the virus, which will be used in future hVivo-run human challenge trials to allow direct comparisons of vaccines or antivirals against different Covid-19 variants.
In virus challenge studies, healthy volunteers are administered a pathogenic or virulent strain of virus.