Keeping time: Understanding the master clock in the brain: Researchers find a molecular pathway that controls sleep rhythms and homeostasis

Researchers found that, in neurons that produced the neuropeptide NMS, the interaction between molecules SIK3 and HDAC4 has a critical role in sleep regulation through both the length of the circadian period and sleep homoeostasis. Given the similarities among different mammals, new information about how the circadian system works in mice could lead to new treatments for sleep and circadian rhythm disorders in humans.

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Tsukuba ,Ibaraki ,Japan ,Masashi Yanagisawa ,Ministry Of Education ,Funding Program For World ,Japan Society For The Promotion Of Science ,Scientific Research ,Japan Agency For Medical Research ,Core Research For Evolutional Science ,World Premier International Research Center Initiative ,University Of Tsukuba ,Technology Agency ,Professor Masashi ,Japan Society ,Japan Science ,Core Research ,Evolutional Science ,Japan Agency ,Medical Research ,Tsukuba Basic Research Support Program Type ,Funding Program ,