Improper DNA division leads to human developmental disorder: Study
ANI |
Updated: Dec 15, 2020 10:36 IST
Birmingham [UK], December 15 (ANI): A recent study by University of Alabama at Birmingham describes a rare genetic developmentdisorder that causes dwarfism, small ears, a small brain, missing patella and other skeletal abnormalities in humans.
The research published as a highlighted article in the Journal Genetics used fruit fly model to reveal about 'Meier-Gorlin' syndrome, or MGS, which is a rare genetic developmental disorder like dwarfism other skeletal abnormalities. In severe cases, MGS even results in miscarriages and stillbirths.
Igor Chesnokov, PhD, and his University of Alabama at Birmingham colleagues study this recessive, autosomal disorder in an unusual way by placing mutant human genes into fruit flies. Specifically, they look at one of the genes involved in MGS called Orc6.