When Bangladesh was first hit by Covid-19 in March/April last year, we all thought that we would be seeing the end of it soon, at most by the year's end. One year down the line, we are rather worse off, not only for the lack of efficient management of the disease but also because of more deadly and virulent variants of the virus which are causing the second wave. This time around, we may be better prepared with more science-based knowledge but so is the virus—armed with various mutations—to penetrate our immune system. It is almost like a war of wits being waged between human ingenuity and the devilish disease, and the battle scene, for the time being, does not look good.